COPD - Types, Causes, Pathophysiology, Symptoms And Management

COPD ( Chronic Obstructive Pulmonary Disease )


The Topic Conclude -

  1. Introduction
  2. World COPD Day
  3. Recent Research And Incidence
  4. Definition Of COPD
  5. Types Of COPD 
  6. Causes Of COPD
  7. Signs And Symptoms Of COPD
  8. Diagnosis Of COPD
  9. Complications Of COPD 
  10. Medical Treatment Of COPD
  11. Nursing Management Of COPD
  12. Nursing Diagnosis On COPD


Adult Health Nursing Notes 3rd Semester
COPD Adult Health Nursing Notes ( 3rd Semester )


Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by chronic inflammation that causes obstructed airflow from the lungs. It is a major cause of morbidity and mortality worldwide and significantly impacts quality of life. The disease includes conditions such as emphysema and chronic bronchitis and is often caused by long-term exposure to irritants, most commonly cigarette smoke.


World COPD Day

World COPD Day is an annual event organized by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) to raise awareness about COPD and improve COPD care globally. World COPD Awareness Day is observed on November 15th each year . It is held on the third Wednesday of November and involves activities such as public health campaigns, educational programs, and advocacy efforts to highlight the burden of COPD and promote measures for prevention and management.


Recent Research and Incidence

Recent research in COPD focuses on early detection, new treatment modalities, and understanding the genetic and environmental factors contributing to the disease. Innovations include advancements in inhaler technologies, biologic therapies targeting specific inflammatory pathways, and regenerative medicine approaches. The incidence of COPD remains high, particularly in regions with high rates of smoking and air pollution. According to the World Health Organization, COPD affects around 251 million people globally and is the third leading cause of death worldwide.


Definition

COPD is defined as a group of lung diseases that block airflow and make breathing difficult. It is characterized by long-term respiratory symptoms and airflow limitation due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases.


Types


1. Chronic Bronchitis

 Defined by chronic productive cough for at least three months in each of two consecutive years. It involves inflammation and excessive mucus production in the bronchial tubes.


Pathophysiology of Chronic Bronchitis

Due to any etiological factors
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Irritation of the Airways
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Hypersecretion of mucous and inflammation
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Favorable environment for growth of microbe 🦠🧫
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Increase production of mucus secreting cell and goblet cell
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More mucus production in the bronchi of airway
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Damage to the surrounding cells and tissues
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Impaired mucociliary action which reduce mucous clearance
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Bronchial wall become thickened and narrow
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Plugging of the airway
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Breathing difficulty
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Chronic Bronchitis


2. Emphysema

 Characterized by damage to the alveoli (air sacs) in the lungs, leading to reduced surface area for gas exchange and respiratory distress.


Pathophysiology 


Due to etiological factor especially smoking

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Increase neutrophils and macrophages

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Deficiency of Alpha-1-antitrypsin

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Increased trypsin

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Imbalance between elastase and protease

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Breakdown of elastin and connective tissue in the lungs

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Destruction of alveolar septa, pulmonary capillaries and loss of plastic recoil of alveoli

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Collapse of the alveoli and septa

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Formation of bullae air pockets between alveolar space and within parenchyma of the lungs

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Airway obstruction and dyspnea

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Impaired gaseous exchange

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Emphysema




Causative Agents

The primary causative agent of COPD is tobacco smoke. Other contributing factors include: 

  • Occupational dust and chemicals (vapors, irritants, and fumes)
  • Air pollution
  • Genetic factors (e.g., Alpha-1 antitrypsin deficiency)
  • Respiratory infections during childhood
  • Chronic Smoking 🚬
  • History of previous respiratory infection such as tuberculosis
  • History of respiratory infection in children 


Risk Factors

  • Smoking (the most significant risk factor)
  • Age (most common in people aged 40 and older)
  • Exposure to occupational dust and chemicals
  • Genetic predisposition (e.g., Alpha-1 antitrypsin deficiency)
  • Chronic respiratory infections
  • Long-term exposure to air pollutants




Signs and Symptoms

  • Chronic cough
  • Sputum production
  • Dyspnea (shortness of breath)
  • Wheezing
  • Chest tightness
  • Frequent respiratory infections
  • Fatigue and reduced exercise capacity
  • Cyanosis (bluish coloration of the lips or fingernails in severe cases)
  • Hypoxemia
  • Hypocapnia 
  • Neck vein distension 


Diagnosis

COPD is diagnosed through a combination of clinical assessment and diagnostic tests:

  • History taking 
  • Physical examination
  • Palpation
  • Auscultation 
  • Spirometry: A lung function test that measures the amount and speed of air a person can inhale and exhale, providing key metrics such as Forced Expiratory Volume in one second (FEV1) and Forced Vital Capacity (FVC).

  • Chest X-ray or CT scan: Imaging studies to visualize lung structure and identify emphysema or other lung conditions.

  • Arterial blood gas analysis: To measure oxygen and carbon dioxide levels in the blood.

  • Alpha-1 antitrypsin deficiency screening: Genetic testing for individuals with a family history of COPD or early-onset disease.



Complications 

  • Acute respiratory failure
  • Pneumonia
  • Right side Heart Failure
  • Pulmonary hypertension


Medical Treatment


1. Pharmacotherapy:


  • Bronchodilators (short-acting and long-acting): To relax muscles around the airways.
  • Inhaled corticosteroids: To reduce inflammation.
  • Combination inhalers: Containing both bronchodilators and corticosteroids.
  • Phosphodiesterase-4 inhibitors: To reduce exacerbations in severe COPD.
  • Antibiotics: For bacterial infections.



2. Oxygen Therapy: For patients with severe COPD and low blood oxygen levels.


3. Pulmonary Rehabilitation: A program of exercise, disease management, and counseling to improve the quality of life.


4. Surgical Interventions: Such as lung volume reduction surgery, bullectomy, or lung transplantation in selected patients.





Nursing Management


1. Assessment: Regular monitoring of respiratory status, including lung sounds, respiratory rate, oxygen saturation, and signs of respiratory distress.


2. Education: Teaching patients about the correct use of inhalers, smoking cessation, and lifestyle modifications.


3. Oxygen Therapy Management: Ensuring the proper use of supplemental oxygen and monitoring for complications.


4. Medication Administration: Administering prescribed medications and monitoring for side effects.


5. Pulmonary Rehabilitation Support: Encouraging participation in rehabilitation programs and providing emotional support.



Nursing Diagnoses According to NANDA


1. Ineffective Airway Clearance:

   - Related to Excessive mucus production and bronchospasm , as evidence  by Dyspnea, wheezing, and ineffective cough.


2. Impaired Gas Exchange:

   - Related to: Alveolar-capillary membrane changes and ventilation-perfusion mismatch , as evidence by Hypoxemia, hypercapnia, and cyanosis.


3. Activity Intolerance:

   - Related to: Imbalance between oxygen supply and demand , as evidence by Dyspnea on exertion, fatigue, and decreased endurance.


4. Anxiety:

   - Related to: Breathlessness and fear of suffocation, evidence by Restlessness, increased heart rate, and verbalization of fear.


5. Deficient Knowledge :

   - Related to: Lack of information about disease management, as evidence by Nonadherence to treatment regimen and incorrect use of inhalers.


Each of these diagnoses guides the development of a comprehensive care plan aimed at improving patient outcomes and quality of life.


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